Determinants of seizure occurrence in preeclampsia before commencing and during treatment with magnesium sulphate
نویسندگان
چکیده
منابع مشابه
Magnesium for seizure prophylaxis in patients with mild preeclampsia.
OBJECTIVE To estimate whether magnesium therapy is the optimal management for women with mild preeclampsia. METHODS A decision analytic model was designed for women with mild preeclampsia to estimate whether empiric magnesium therapy or no magnesium therapy is the optimal management strategy. The model considered relevant clinical events: seizure, placental abruption, and magnesium toxicity. ...
متن کاملTreatment of Eclampsia with Magnesium Sulphate
Backerganj circulated a pamphlet suggesting magnesium sulphate injections for the treatment of eclampsia. Roy (1941) treated some cases with intravenous injection of 15 c.cm. of 10 per cent solution of magnesium sulphate, along with StroganofFs treatment, intravenous glucose, etc. I have treated 15 cases of which only two died. In all these I injected 5 c.cm. of 25 per cent solution of magnesiu...
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Hypermagnesemia is a rare and under-recognized cause of paralytic ileus. We report a case of a 21-year-old primigravida who was managed aggressively for preeclampsia and presented with postpartum paralytic ileus. Detailed history was employed to consider hypermagnesemia-induced ileus as the working diagnosis, and the patient improved with correction of the electrolyte imbalance. Hypermagnesemia...
متن کاملMagnesium Sulfate Treatment Reverses Seizure Susceptibility and Decreases Neuroinflammation in a Rat Model of Severe Preeclampsia
Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO4) is the leading eclamptic seizure prophylactic, yet its mechanism of action remains unclear. Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and...
متن کاملThe comparison of anti-seizure and tocolytic effects of phenytoin and magnesium sulphate in the treatment of eclampsia and preeclampsia: A randomised clinical trial
Background: To date, magnesium sulphate (MgSO4) is the treatment of choice for prevention of seizure in eclampsia and preeclampsia. However, there are some limitations in the administration of MgSO4 due to its tocolytic effects. The aim of this study was to compare the anticonvulsant and tocolytic effects of MgSO4 and another drug, phenytoin, in patients with eclampsia and preeclampsia. Methods...
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ژورنال
عنوان ژورنال: International Journal of Reproduction, Contraception, Obstetrics and Gynecology
سال: 2016
ISSN: 2320-1770
DOI: 10.18203/2320-1770.ijrcog20163404